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Does Clonidine Show Up on a DOT Drug Test?

Written by Nick Webster

Published on Dec. 11, 2023, 2:44 p.m.

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Does Clonidine Show Up on a DOT Drug Test?






Does clonidine show up on a DOT drug test?” is an excellent question. Clonidine is a medication that is used to treat:






  • high blood pressure
  • attention deficit hyperactivity disorder (ADHD)
  • anxiety
  • hot flashes


It is not typically used as an illicit drug, so it does not usually show up on a DOT (Department of Transportation) drug test. However, a positive result for clonidine may appear if the individual has been taking higher than recommended doses of the medication or has combined it with other drugs that could be detected on the test. Take a look at the Drug and Alcohol Program policy.

Therefore, people who are taking clonidine should always inform their doctor before undergoing any type of drug screening. Additionally, healthcare providers should take into consideration all off-label prescriptions and supplements when administering DOT drug tests. Please continue reading to learn more about clonidine and DOT drug testing.



How Long Will Clonidine Stay in Your System?



Clonidine can stay in your system for up to five days after the last dose. The amount of time that clonidine stays in the body influences how long it takes for its effects to wear off, so knowing how long it's in your system is important.

When taking clonidine, it starts working immediately and is fully absorbed into the bloodstream within 30 minutes. This means that its effects will be felt quickly but they may also wear off quickly if too much gets eliminated from the body.



What Impacts How Long Clonidine Will Stay in My System?




Clonidine stays in your system for different amounts of time depending on a variety of factors:

  • Your age, body weight, and general health status can affect how quickly your body processes and eliminates clonidine. Generally speaking, older adults have slower metabolisms than younger people and may take longer to metabolize clonidine. Also, visit the link.
  • The dosage of clonidine prescribed by your doctor also affects the length of time it stays in your system. Higher doses tend to stay in the body longer than lower doses.
  • If you are taking any medications or supplements that interact with clonidine, this could influence the amount of time it remains in your system. Be sure to speak with your doctor about the effects of clonidine. Check out the DOT Compliant Drug and Alcohol Program.




What Drugs Does DOT Drug Testing Detect?



DOT drug tests detect five different classes of drugs:

  • Marijuana
  • Cocaine
  • Opioids (such as heroin, codeine, and morphine)
  • Amphetamines (including methamphetamines)
  • Phencyclidine (PCP)

These substances are measured in nanograms per milliliter (ng/mL). A positive test result is when the concentration of a tested substance exceeds the established cutoff level. The Department of Transportation also encourages employers to consider adding other substances to their testing panels such as barbiturates, benzodiazepines, propoxyphene, and other prescription drugs.



How Long Does It Take for Clonidine To Work?



This medicine comes in two forms: immediate-release and extended-release. If you take the IR version, you can expect peak blood levels of it to reach their max in between one to five hours. That's pretty swift! Get ready for the effects to kick in soon after taking it. You will need driver qualification files filed out by all employees that drive for you working.

If you've got a little one under six years old, steer clear of the ER type. You're gonna get far lower concentration levels than with the IR formulation and they're gonna arrive a full five hours later! That's something to consider when deciding which formula is right for your family. But regardless of what method you go with, make sure it fits in with their developmental stage and age so that everyone stays safe and healthy. Ultimately, that's what matters most. Visit DOT Authority Package, Tips to prepare for 2023 DOT Week filings in minutes.



How Long Do the Effects of Clonidine Last?



Whoa, Clonidine is a fast-acting drug! It's quickly absorbed, and you can expect to feel its effects within just 1-3 hours. Even better – you'll get the blood pressure-lowering effect in as little as 30 minutes after taking it. The maximum effect on blood pressure for this stuff occurs within 2-4 hours, so keep your fingers crossed that it works immediately! What is DOT Clearinghouse Enforcement?



Can Clonidine Show Up on a DOT Urine Test?



Yes. Clonidine can show up on a urine test. It's important to be aware of this if you're taking clonidine for any condition. Knowing this information could save you from a lot of confusion or embarrassment down the line. So, if you take clonidine, make sure to tell the person responsible for your DOT drug test so he or she knows to look out for it when doing a urine test! It’s also important to note that other drugs like opiates, benzodiazepines, amphetamines, methamphetamines, and other synthetic drugs can also be detected by urine tests. Read about Texas DOT Numbers and USDOT Numbers. Learn here How to Prepare for a Compliance DOT Audit.



Is Clonidine a Controlled Substance?



Yes, clonidine is a controlled substance. It's classified as a Schedule IV drug by the Drug Enforcement Administration (DEA) and it has the potential for Abuse and dependence. However, when used under medical supervision and taken in appropriate doses, it can be an effective treatment for high blood pressure, ADHD, hot flashes and other conditions. So if you're prescribed this medication by your doctor, make sure you follow their instructions to stay safe! Visit BOC-3 to know more.



Summary: Will Clonidine Appear on a DOT Drug Test?



  • Clonidine does not show up directly on a DOT drug test as it is not included in the list of substances tested.
  • It is generally not tested for, even if it is suspected that an individual may have been using clonidine or other drugs, as this type of drug testing is specific to certain categories and types of drugs.
  • The most common tests to detect clonidine are urine and blood tests. Urine tests look for metabolites produced when the body breaks down the drug, while blood tests measure the amount of clonidine in the bloodstream.
  • If there is suspicion that someone has taken clonidine, a doctor may order additional testing, such as hair follicle testing.
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